CHEM 440 - Physical Chemistry and Bioinformatics of Macromolecules

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Structure and function relationships of biological macromolecules from a physical and informatics perspective involving the study of structural transitions and intermolecular interactions as well as properties of macromolecular assemblies elucidated by the study of database mining techniques, molecular visualization techniques and physical techniques. Physical techniques will include optical spectroscopy, magnetic resonance, hydrodynamics, scattering and diffraction. Numerous methodologies of bioinformatics will be explored, focusing on answering questions in biochemistry, elucidating how structure/function questions map to computational problems and yield resulting solutions. Prerequisite: CHEM 436. Spring.